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Conserved domains on  [gi|1464309416|ref|YP_009507707|]
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VP1 [Lebombo virus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Orbi_VP1 super family cl12314
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 29-1293 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


The actual alignment was detected with superfamily member pfam05788:

Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1126.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416   29 YYYYRFSSNMREIRRKKGVVYGKSDEQIIRERERGTLRLYGIEVIREATWEEVL-GEPQGSDALQIYMRSLLDHEDLEPE 107
Cdd:pfam05788   32 CYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKYVFdGQTFQSYAFEVYVNSILPWSELDPE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  108 EEFLRNYRVVEPDSAMSKFIEMRAKSEMQIYGDMPIRFWAGLIEEISVTLKHVPLGLDVMRQFVrdygsPFDQNTRDLSH 187
Cdd:pfam05788  112 EEFLRNYRVSREKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIELGMQPLGMQVMADFV-----NRFQSPFHQGN 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  188 LENFRVSYSTPLLFEMCCAESLLEFNMLLRMEEEKIKNLEFGGKRINPYDVIREFFIVALPHPKKINNMLRSPYSWAVKV 267
Cdd:pfam05788  187 RDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKLDPVGLLREFFILCLPHPKKINNVLRAPYS 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  268 WGVAAEDIVILESIGGEDRNSKEVYYKSFSRVKNPYSSMLTKSlFYASSLKDNVAKVNDAIKYSNDLGNHEKGLPIFQSM 347
Cdd:pfam05788  267 WFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRYKA-LFRSSFYNESRRMNEEKILEAVKYSQDLGSHDRRLP 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  348 LESIYSTPFDPSNIKHVILASLLLSIQVMTGYGRAWVMN------KPSGDDQMKPAADNFIERVNDYTKQFFIQAYHEAK 421
Cdd:pfam05788  346 LFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRawvknvSTEFDKQLKPNPSNLVLDVSDLTREFFKQAYVEAK 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  422 VSGEEIVKPEDMYTSILRLARNTSSGFSTSVDVYKRYGPKAGKFgEKIKITSRIKALVIFVEGHKVFTRDNLLRKYNSTE 501
Cdd:pfam05788  426 ERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKKRFGPRLRDK-DLRKINSRIKALVIFTKGHTVFTDEELHKKYNSVE 504

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  502 FYQSKGSRDVPIKSTRTIYSINLSILVPQLIVTLPLNEYFAHAGGSTLPKSTRLAGKVIIGDLEATGSRVVDAADTFRNS 581
Cdd:pfam05788  505 LYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDYKKIGGKVIVGDLEATGSRVMDAADCFRNS 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  582 SDPDILTIAIDYSDYDQHLTVHNFRKGMLDGIRSAMQPYAHLRYEGFSLDEIIDFGYGEGRVVNSLWNGKRRVFKVSFSS 661
Cdd:pfam05788  585 ADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTFDA 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  662 YLMLSDDERQQGMFKPPIGVKPVSGMHVIDKL-DTQGTDyILVAPTDGSDLAMINTHLSGENSTLVANSLHNMAIGRTIQ 740
Cdd:pfam05788  665 YIRLDESERDKGSFKVPKGVLPVSSVDVANRIaVDKGFD-TLIAATDGSDLALIDTHLSGENSTLIANSMHNMAIGTLGQ 743

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  741 EEVrahhrGALEVLSEQYVGDDTLFYTKLHTRDPVIFDRIVQTIFDTVAKCGHEASPAKTLIAPFSVEKTQTHAKQGIYI 820
Cdd:pfam05788  744 RQV-----GREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEKTQTHAK 818

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  821 PQDRMMLISSERRKDIENVQGYMRSQAQTMVTKVSRGFSSRLANIIFMAKGSTIGYRKMKRTLLEGGVFRDRKFDSNEED 900
Cdd:pfam05788  819 QGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKTTFIGAWKMKRTIKEDAMYRDRKFD 898

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  901 GFTLLQIRDPLTSFLPTEWGGYGLHPAAMNLVMTEDLLLDSMRFGVIYDAMRMLTKFGGVRLPVWDETKADKRMIATDTQ 980
Cdd:pfam05788  899 SNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVHDIPPCWNETQGDKRGL 978

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  981 MGFFSKMARPAVRMTFEHAALADEVKKLPLGDYSPFNLSRTMMHGALLKESAARSLLAPAYEGEYQSELNSsKLASFSLS 1060
Cdd:pfam05788  979 ISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKESSASGLLSSGYKLEYQ-KALNVWIR 1057

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1061 AGNMEL--STNYAKTFEVTFVNALTNQTFTFPDQNISPN-----FFVQKALLGPRVSSRVRMSYIDRLDSILRGDVVMRG 1133
Cdd:pfam05788 1058 QVSMRLgeESGVISTSYAKLFDVYFEGELDGAPQMFPDQnlspqFYIQKMMIGPRVSSRVRNSYVDRIDVILRKDVVMRG 1137

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1134 TLTANTIMNVLEKIGHSHGVSELTTVFQLMNIEDRVAQRLAEYIAAERVKFDALKLIKRGVGGDEFTMSLDVCTQTMVER 1213
Cdd:pfam05788 1138 FITANTILNVIEKLGTNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQDFIDT 1217

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1214 FARYPPQFTKSEVDMTILYITQLLILQAVAEGRVKRVDVNVSAEAKVRQKQREARFKTHLPRLRVVNKLMNVDRLSARMV 1293
Cdd:pfam05788 1218 YLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKIRLQRFRTHVPKIKVLKKLIDPNRMTVRNL 1297
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 29-1293 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1126.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416   29 YYYYRFSSNMREIRRKKGVVYGKSDEQIIRERERGTLRLYGIEVIREATWEEVL-GEPQGSDALQIYMRSLLDHEDLEPE 107
Cdd:pfam05788   32 CYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKYVFdGQTFQSYAFEVYVNSILPWSELDPE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  108 EEFLRNYRVVEPDSAMSKFIEMRAKSEMQIYGDMPIRFWAGLIEEISVTLKHVPLGLDVMRQFVrdygsPFDQNTRDLSH 187
Cdd:pfam05788  112 EEFLRNYRVSREKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIELGMQPLGMQVMADFV-----NRFQSPFHQGN 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  188 LENFRVSYSTPLLFEMCCAESLLEFNMLLRMEEEKIKNLEFGGKRINPYDVIREFFIVALPHPKKINNMLRSPYSWAVKV 267
Cdd:pfam05788  187 RDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKLDPVGLLREFFILCLPHPKKINNVLRAPYS 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  268 WGVAAEDIVILESIGGEDRNSKEVYYKSFSRVKNPYSSMLTKSlFYASSLKDNVAKVNDAIKYSNDLGNHEKGLPIFQSM 347
Cdd:pfam05788  267 WFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRYKA-LFRSSFYNESRRMNEEKILEAVKYSQDLGSHDRRLP 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  348 LESIYSTPFDPSNIKHVILASLLLSIQVMTGYGRAWVMN------KPSGDDQMKPAADNFIERVNDYTKQFFIQAYHEAK 421
Cdd:pfam05788  346 LFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRawvknvSTEFDKQLKPNPSNLVLDVSDLTREFFKQAYVEAK 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  422 VSGEEIVKPEDMYTSILRLARNTSSGFSTSVDVYKRYGPKAGKFgEKIKITSRIKALVIFVEGHKVFTRDNLLRKYNSTE 501
Cdd:pfam05788  426 ERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKKRFGPRLRDK-DLRKINSRIKALVIFTKGHTVFTDEELHKKYNSVE 504

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  502 FYQSKGSRDVPIKSTRTIYSINLSILVPQLIVTLPLNEYFAHAGGSTLPKSTRLAGKVIIGDLEATGSRVVDAADTFRNS 581
Cdd:pfam05788  505 LYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDYKKIGGKVIVGDLEATGSRVMDAADCFRNS 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  582 SDPDILTIAIDYSDYDQHLTVHNFRKGMLDGIRSAMQPYAHLRYEGFSLDEIIDFGYGEGRVVNSLWNGKRRVFKVSFSS 661
Cdd:pfam05788  585 ADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTFDA 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  662 YLMLSDDERQQGMFKPPIGVKPVSGMHVIDKL-DTQGTDyILVAPTDGSDLAMINTHLSGENSTLVANSLHNMAIGRTIQ 740
Cdd:pfam05788  665 YIRLDESERDKGSFKVPKGVLPVSSVDVANRIaVDKGFD-TLIAATDGSDLALIDTHLSGENSTLIANSMHNMAIGTLGQ 743

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  741 EEVrahhrGALEVLSEQYVGDDTLFYTKLHTRDPVIFDRIVQTIFDTVAKCGHEASPAKTLIAPFSVEKTQTHAKQGIYI 820
Cdd:pfam05788  744 RQV-----GREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEKTQTHAK 818

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  821 PQDRMMLISSERRKDIENVQGYMRSQAQTMVTKVSRGFSSRLANIIFMAKGSTIGYRKMKRTLLEGGVFRDRKFDSNEED 900
Cdd:pfam05788  819 QGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKTTFIGAWKMKRTIKEDAMYRDRKFD 898

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  901 GFTLLQIRDPLTSFLPTEWGGYGLHPAAMNLVMTEDLLLDSMRFGVIYDAMRMLTKFGGVRLPVWDETKADKRMIATDTQ 980
Cdd:pfam05788  899 SNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVHDIPPCWNETQGDKRGL 978

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  981 MGFFSKMARPAVRMTFEHAALADEVKKLPLGDYSPFNLSRTMMHGALLKESAARSLLAPAYEGEYQSELNSsKLASFSLS 1060
Cdd:pfam05788  979 ISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKESSASGLLSSGYKLEYQ-KALNVWIR 1057

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1061 AGNMEL--STNYAKTFEVTFVNALTNQTFTFPDQNISPN-----FFVQKALLGPRVSSRVRMSYIDRLDSILRGDVVMRG 1133
Cdd:pfam05788 1058 QVSMRLgeESGVISTSYAKLFDVYFEGELDGAPQMFPDQnlspqFYIQKMMIGPRVSSRVRNSYVDRIDVILRKDVVMRG 1137

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1134 TLTANTIMNVLEKIGHSHGVSELTTVFQLMNIEDRVAQRLAEYIAAERVKFDALKLIKRGVGGDEFTMSLDVCTQTMVER 1213
Cdd:pfam05788 1138 FITANTILNVIEKLGTNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQDFIDT 1217

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1214 FARYPPQFTKSEVDMTILYITQLLILQAVAEGRVKRVDVNVSAEAKVRQKQREARFKTHLPRLRVVNKLMNVDRLSARMV 1293
Cdd:pfam05788 1218 YLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKIRLQRFRTHVPKIKVLKKLIDPNRMTVRNL 1297
 
Name Accession Description Interval E-value
Orbi_VP1 pfam05788
Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA ...
 29-1293 0e+00

Orbivirus RNA-dependent RNA polymerase (VP1); This family consists of the RNA-dependent RNA polymerase protein VP1 from the Orbiviruses. VP1 may have both enzymatic and structural roles in the virus life cycle.


Pssm-ID: 461740  Cd Length: 1297  Bit Score: 1126.72  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416   29 YYYYRFSSNMREIRRKKGVVYGKSDEQIIRERERGTLRLYGIEVIREATWEEVL-GEPQGSDALQIYMRSLLDHEDLEPE 107
Cdd:pfam05788   32 CYIYKFSDHIRRIRMKHGTKYRRQAEEILRKISLRKERLYGIPVLDEVEWKYVFdGQTFQSYAFEVYVNSILPWSELDPE 111

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  108 EEFLRNYRVVEPDSAMSKFIEMRAKSEMQIYGDMPIRFWAGLIEEISVTLKHVPLGLDVMRQFVrdygsPFDQNTRDLSH 187
Cdd:pfam05788  112 EEFLRNYRVSREKTEVEKFIEFRAKNEMQIYGDIPIKVWCCFINELSIELGMQPLGMQVMADFV-----NRFQSPFHQGN 186

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  188 LENFRVSYSTPLLFEMCCAESLLEFNMLLRMEEEKIKNLEFGGKRINPYDVIREFFIVALPHPKKINNMLRSPYSWAVKV 267
Cdd:pfam05788  187 RDLSNLEDFQVAYTTPLLFEMCCMESILEFNIKMRMREEEISALEFGDVKLDPVGLLREFFILCLPHPKKINNVLRAPYS 266

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  268 WGVAAEDIVILESIGGEDRNSKEVYYKSFSRVKNPYSSMLTKSlFYASSLKDNVAKVNDAIKYSNDLGNHEKGLPIFQSM 347
Cdd:pfam05788  267 WFVKMWGVGADPIVVLQSTAGDDRNSKDVFYDKFRTEPNRYKA-LFRSSFYNESRRMNEEKILEAVKYSQDLGSHDRRLP 345

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  348 LESIYSTPFDPSNIKHVILASLLLSIQVMTGYGRAWVMN------KPSGDDQMKPAADNFIERVNDYTKQFFIQAYHEAK 421
Cdd:pfam05788  346 LFEKMLKPVYTTPFYPHKSSNMILASFLLSIQTITGYGRawvknvSTEFDKQLKPNPSNLVLDVSDLTREFFKQAYVEAK 425

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  422 VSGEEIVKPEDMYTSILRLARNTSSGFSTSVDVYKRYGPKAGKFgEKIKITSRIKALVIFVEGHKVFTRDNLLRKYNSTE 501
Cdd:pfam05788  426 ERREEDVKPEDLYTSMLRLARNTSSGFSTEIYVKKRFGPRLRDK-DLRKINSRIKALVIFTKGHTVFTDEELHKKYNSVE 504

                          490       500       510       520       530       540       550       560
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  502 FYQSKGSRDVPIKSTRTIYSINLSILVPQLIVTLPLNEYFAHAGGSTLPKSTRLAGKVIIGDLEATGSRVVDAADTFRNS 581
Cdd:pfam05788  505 LYQTKGSRDVPIKATRTIYSINLSVLVPQLIVTLPLNEYFSRVGGITKPDYKKIGGKVIVGDLEATGSRVMDAADCFRNS 584

                          570       580       590       600       610       620       630       640
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  582 SDPDILTIAIDYSDYDQHLTVHNFRKGMLDGIRSAMQPYAHLRYEGFSLDEIIDFGYGEGRVVNSLWNGKRRVFKVSFSS 661
Cdd:pfam05788  585 ADRDIFTIAIDYSEYDTHLTRHNFRTGMLQGIREAMAPYRGLRYEGYTLEQIIDFGYGEGRVANTLWNGKRRLFKTTFDA 664

                          650       660       670       680       690       700       710       720
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  662 YLMLSDDERQQGMFKPPIGVKPVSGMHVIDKL-DTQGTDyILVAPTDGSDLAMINTHLSGENSTLVANSLHNMAIGRTIQ 740
Cdd:pfam05788  665 YIRLDESERDKGSFKVPKGVLPVSSVDVANRIaVDKGFD-TLIAATDGSDLALIDTHLSGENSTLIANSMHNMAIGTLGQ 743

                          730       740       750       760       770       780       790       800
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  741 EEVrahhrGALEVLSEQYVGDDTLFYTKLHTRDPVIFDRIVQTIFDTVAKCGHEASPAKTLIAPFSVEKTQTHAKQGIYI 820
Cdd:pfam05788  744 RQV-----GREQPGSLTFLSEQYVGDDTLFYTKLHTTDKVVFDKVAASIFDTVAKCGHEASPSKTMMTPYSVEKTQTHAK 818

                          810       820       830       840       850       860       870       880
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  821 PQDRMMLISSERRKDIENVQGYMRSQAQTMVTKVSRGFSSRLANIIFMAKGSTIGYRKMKRTLLEGGVFRDRKFDSNEED 900
Cdd:pfam05788  819 QGCYVPQDRMMIISSERRKDIEDVQGYVRSQVQTMITKVSRGFCHDLAQLILMLKTTFIGAWKMKRTIKEDAMYRDRKFD 898

                          890       900       910       920       930       940       950       960
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  901 GFTLLQIRDPLTSFLPTEWGGYGLHPAAMNLVMTEDLLLDSMRFGVIYDAMRMLTKFGGVRLPVWDETKADKRMIATDTQ 980
Cdd:pfam05788  899 SNDEDGFTLIQIRNPLALYVPIGWNGYGAHPAALNIVMTEEMYVDSIMISKLDEIMAPIRRIVHDIPPCWNETQGDKRGL 978

                          970       980       990      1000      1010      1020      1030      1040
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416  981 MGFFSKMARPAVRMTFEHAALADEVKKLPLGDYSPFNLSRTMMHGALLKESAARSLLAPAYEGEYQSELNSsKLASFSLS 1060
Cdd:pfam05788  979 ISATKKSFFSKMARPAVQAALSDPQIENLVEELPLGEFSPGRISRTMMHSALLKESSASGLLSSGYKLEYQ-KALNVWIR 1057

                         1050      1060      1070      1080      1090      1100      1110      1120
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1061 AGNMEL--STNYAKTFEVTFVNALTNQTFTFPDQNISPN-----FFVQKALLGPRVSSRVRMSYIDRLDSILRGDVVMRG 1133
Cdd:pfam05788 1058 QVSMRLgeESGVISTSYAKLFDVYFEGELDGAPQMFPDQnlspqFYIQKMMIGPRVSSRVRNSYVDRIDVILRKDVVMRG 1137

                         1130      1140      1150      1160      1170      1180      1190      1200
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1134 TLTANTIMNVLEKIGHSHGVSELTTVFQLMNIEDRVAQRLAEYIAAERVKFDALKLIKRGVGGDEFTMSLDVCTQTMVER 1213
Cdd:pfam05788 1138 FITANTILNVIEKLGTNHSVGDLVTVFTLMNIETRVAEELAEYMTSEKIRFDALKLLKKGIAGDEFTMSLNVATQDFIDT 1217

                         1210      1220      1230      1240      1250      1260      1270      1280
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1464309416 1214 FARYPPQFTKSEVDMTILYITQLLILQAVAEGRVKRVDVNVSAEAKVRQKQREARFKTHLPRLRVVNKLMNVDRLSARMV 1293
Cdd:pfam05788 1218 YLAYPYQLTKTEVDAISLYCTQMAMLRAALGLPKKKMKIVVTDDAKKRYKIRLQRFRTHVPKIKVLKKLIDPNRMTVRNL 1297
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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