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Conserved domains on  [gi|1693285542|ref|YP_009647940|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Isophya major]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009599)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 1-171 3.96e-30

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214445  Cd Length: 160  Bit Score: 107.58  E-value: 3.96e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542   1 MQFTFIPSLLITFIFLFTSHPLTMTLTIVAQTLLVCLTTNTLSQTFWFSYILFLVFLGGMLVLFIYITSLAANEMFTSMM 80
Cdd:MTH00166    1 KMMLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542  81 KIISLNLILITMIFLTTNLLDPFIINPFSTNSDTLEMSlqpipysevhhlLIKLYNTPTKLLTLMLVCYLFFTLIAVVKI 160
Cdd:MTH00166   81 KLLILFLLMLLLMLNNFIKNSEMSNFNNNFNFFENSFS------------LSKLYNFPTMLITLFMIIYLLLTLIVVVKI 148

                         170
                  ....*....|.
gi 1693285542 161 TNIFLGPLRQK 171
Cdd:MTH00166  149 TNIFKGPLRSK 159
 
Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 1-171 3.96e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 107.58  E-value: 3.96e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542   1 MQFTFIPSLLITFIFLFTSHPLTMTLTIVAQTLLVCLTTNTLSQTFWFSYILFLVFLGGMLVLFIYITSLAANEMFTSMM 80
Cdd:MTH00166    1 KMMLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542  81 KIISLNLILITMIFLTTNLLDPFIINPFSTNSDTLEMSlqpipysevhhlLIKLYNTPTKLLTLMLVCYLFFTLIAVVKI 160
Cdd:MTH00166   81 KLLILFLLMLLLMLNNFIKNSEMSNFNNNFNFFENSFS------------LSKLYNFPTMLITLFMIIYLLLTLIVVVKI 148

                         170
                  ....*....|.
gi 1693285542 161 TNIFLGPLRQK 171
Cdd:MTH00166  149 TNIFKGPLRSK 159
 
Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 1-171 3.96e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 107.58  E-value: 3.96e-30
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542   1 MQFTFIPSLLITFIFLFTSHPLTMTLTIVAQTLLVCLTTNTLSQTFWFSYILFLVFLGGMLVLFIYITSLAANEMFTSMM 80
Cdd:MTH00166    1 KMMLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542  81 KIISLNLILITMIFLTTNLLDPFIINPFSTNSDTLEMSlqpipysevhhlLIKLYNTPTKLLTLMLVCYLFFTLIAVVKI 160
Cdd:MTH00166   81 KLLILFLLMLLLMLNNFIKNSEMSNFNNNFNFFENSFS------------LSKLYNFPTMLITLFMIIYLLLTLIVVVKI 148

                         170
                  ....*....|.
gi 1693285542 161 TNIFLGPLRQK 171
Cdd:MTH00166  149 TNIFKGPLRSK 159
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 1-172 5.18e-10

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 55.01  E-value: 5.18e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542   1 MQFTFIPSLLITFIFLFTSHPLTMTLTIVAQTLLVCLTTnTLSQTFWFSYILFLVFLGGMLVLFIYITSLAANEMFTSMM 80
Cdd:MTH00212    3 LSLLLSLLLLLMLLFPLSAHPLTLGVSLLLSSLLSCLII-TMESNSWYGYILFLIYIGGLLVLFGYMVALSPNEHLFFKK 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542  81 KIISLNLILITMIFLttnlldpFIINPFSTNSDTLEMSLQPIPYsevhhlLIKLYNTPTKLLTLMLVCYLFFTLIAVVKI 160
Cdd:MTH00212   82 YFKGFGMILISLNLY-------LLLMTLGSSNFSPMLNLKLELN------VSKILSNNNIPILLFLGLILLIALLMVVKI 148

                         170
                  ....*....|..
gi 1693285542 161 TNIFLGPLRQKY 172
Cdd:MTH00212  149 CQYYKGPLRPFL 160
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 13-169 2.65e-08

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 50.66  E-value: 2.65e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542  13 FIFLFTSHPLTMTLTIVAQTLLVCLTTnTLSQTFWFSYILFLVFLGGMLVLFIYITSLAANEMFTSMMKIISLNLILITM 92
Cdd:MTH00152   15 LLLPLSKQPLSLGLVLLLLSLFVCVEI-GLTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGSNFKFVFFSLTLFGF 93

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 1693285542  93 IFLttnlldpFIINPFSTNSDTLEMSLQPIPYSEVHHLLIKLYNTPTKLLTLMLVCYLFFTLIAVVKITNIFLGPLR 169
Cdd:MTH00152   94 LGL-------FFFFLYLYSSGGLSLSSLFDGSSGSLSFGGGLYSSSGWSIFVFLAVLLLIVMVSVVKICYYEEGSLR 163
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 49-72 1.14e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 40.51  E-value: 1.14e-04
                          10        20
                  ....*....|....*....|....
gi 1693285542  49 SYILFLVFLGGMLVLFIYITSLAA 72
Cdd:MTH00138   52 SLVLFLIYLGGMLVVFAYSAALAA 75
PTZ00243 PTZ00243
ABC transporter; Provisional
 8-162 3.74e-04

ABC transporter; Provisional


Pssm-ID: 240327 [Multi-domain]  Cd Length: 1560  Bit Score: 40.15  E-value: 3.74e-04
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542    8 SLLITFIFLFTShpltmTLTIVAQTLLVCLTTNT--LSQTFWFSYILFLVFLGGMLVLFIYITSLAANEMFTSMMKIISL 85
Cdd:PTZ00243   964 AGFVLATFAVTE-----LVTVSSGVWLSMWSTRSfkLSAATYLYVYLGIVLLGTFSVPLRFFLSYEAMRRGSRNMHRDLL 1038

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542   86 NLILI-TMIFLTTNLLDPfIINPFSTNSDTLEMSLQ-------PIPYSEVHHLLIKLYNTPTKLLTLMLVCYLFFTLIAV 157
Cdd:PTZ00243  1039 RSVSRgTMSFFDTTPLGR-ILNRFSRDIDILDNTLPmsylyllQCLFSICSSILVTSASQPFVLVALVPCGYLYYRLMQF 1117


                   ....*
gi 1693285542  158 VKITN 162
Cdd:PTZ00243  1118 YNSAN 1122
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 49-72 9.47e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 37.91  E-value: 9.47e-04
                          10        20
                  ....*....|....*....|....
gi 1693285542  49 SYILFLVFLGGMLVLFIYITSLAA 72
Cdd:MTH00065   52 SLVLFLIYLGGMLVVFAYSAALAA 75
ND6 MTH00015
NADH dehydrogenase subunit 6; Validated
 1-169 1.37e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 164590  Cd Length: 155  Bit Score: 37.53  E-value: 1.37e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542   1 MQFTFIPSLLITFIFLFTSHPLTMTLTIVAQTLLVClTTNTLSQTFWFSYILFLVFLGGMLVLFIYITSLAANEmftsmm 80
Cdd:MTH00015    3 LSFFLILMISLTCSLFLATTPITLGINILMMALLLA-TTMASALSSWFAFLTFLIYVGGMLVMFAYFLALTPNQ------ 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1693285542  81 KIISLNLILITMIFLTTNLLDPFIINPFSTNSDTLEMSLQpipysevhhlliKLYNTPTKLLTLMLVCYLFFTLIAVVKI 160
Cdd:MTH00015   76 QLNLGPMAKYTLITLLTLSTTLKLTNPPSPSFFSSTQGNT------------FLYQPENAPLLIFLALILLLTMVIVVKL 143


                  ....*....
gi 1693285542 161 TNIFLGPLR 169
Cdd:MTH00015  144 TRRSSGPLR 152
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 47-72 7.07e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 35.49  E-value: 7.07e-03
                          10        20
                  ....*....|....*....|....*.
gi 1693285542  47 WFSYILFLVFLGGMLVLFIYITSLAA 72
Cdd:MTH00115   50 FVSLVLFLVYLGGMLVVFAYSVSLAA 75
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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