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Conserved domains on  [gi|58045512|ref|YP_192897|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Gryllotalpa orientalis]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 5-92 2.27e-21

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 80.20  E-value: 2.27e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   5 YYIVVFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFSMVFLTFSVCEGALGLAVLVSIIRT 84
Cdd:MTH00162  2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                ....*...
gi 58045512  85 HGNDYFHS 92
Cdd:MTH00162 82 HGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 5-92 2.27e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 80.20  E-value: 2.27e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   5 YYIVVFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFSMVFLTFSVCEGALGLAVLVSIIRT 84
Cdd:MTH00162  2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                ....*...
gi 58045512  85 HGNDYFHS 92
Cdd:MTH00162 82 HGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 1.32e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.95  E-value: 1.32e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512    5 YYIVVFYLMFFAGAWMFISkRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYEL--YFSMVFLTFSVCEGALGLAVLVSII 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 58045512   83 RTHGNDYFHSISMLKC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 5-92 2.27e-21

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 80.20  E-value: 2.27e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   5 YYIVVFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFSMVFLTFSVCEGALGLAVLVSIIRT 84
Cdd:MTH00162  2 MMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIRS 81


                ....*...
gi 58045512  85 HGNDYFHS 92
Cdd:MTH00162 82 HGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 7-98 2.19e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 62.68  E-value: 2.19e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   7 IVVFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFSMVFLTFSVCEGALGLAVLVSIIRTHG 86
Cdd:MTH00188  6 ILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSLIRSHG 85

                        90
                ....*....|..
gi 58045512  87 NDYFHSISMLKC 98
Cdd:MTH00188 86 SDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 10-98 3.87e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 62.17  E-value: 3.87e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512  10 FYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFSM--VFLTFSVCEGALGLAVLVSIIRTHGN 87
Cdd:MTH00125  8 LYTAFMLSLLGLSFHRTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTPMpiILLTFSACEAGTGLALLVATTRTHGS 87

                        90
                ....*....|.
gi 58045512  88 DYFHSISMLKC 98
Cdd:MTH00125 88 DHLKNLNLLQC 98
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 8-98 1.47e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 60.63  E-value: 1.47e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   8 VVFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFSMVFLTFSVCEGALGLAVLVSIIRTHGN 87
Cdd:MTH00149  7 LLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSLIRLHGN 86

                        90
                ....*....|.
gi 58045512  88 DYFHSISMLKC 98
Cdd:MTH00149 87 DYVSSLSSLKF 97
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 25-98 1.79e-13

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 60.36  E-value: 1.79e-13
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 58045512  25 RKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFS--MVFLTFSVCEGALGLAVLVSIIRTHGNDYFHSISMLKC 98
Cdd:MTH00126 23 RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFSAapMLLLAFSACEASAGLALLVATARTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 10-98 1.33e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 58.08  E-value: 1.33e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512  10 FYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFS--MVFLTFSVCEGALGLAVLVSIIRTHGN 87
Cdd:MTH00067  8 FYSAFLLGLMGLAFHRTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFSlpMFMLTFSACEASTGLALMVATTRTHGT 87

                        90
                ....*....|.
gi 58045512  88 DYFHSISMLKC 98
Cdd:MTH00067 88 DHLKNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
5-98 1.32e-10

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 52.95  E-value: 1.32e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512    5 YYIVVFYLMFFAGAWMFISkRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYEL--YFSMVFLTFSVCEGALGLAVLVSII 82
Cdd:pfam00420  1 AYLLLSGLLFLIGLYGLLL-RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIY 79

                         90
                 ....*....|....*.
gi 58045512   83 RTHGNDYFHSISMLKC 98
Cdd:pfam00420 80 RTHGTDDVDSLNLLKG 95
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 9-98 1.36e-10

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 52.83  E-value: 1.36e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   9 VFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLI-EGYELYFSMVFLTFSVCEGALGLAVLVSIIRTHGN 87
Cdd:MTH00013  7 ILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLMFaNQVNGMLAIVLLTFGACEASLGLSLLVLMTRSYGN 86

                        90
                ....*....|.
gi 58045512  88 DYFHSISMLKC 98
Cdd:MTH00013 87 DMLKSLTSNKC 97
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 7-98 1.21e-09

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 50.70  E-value: 1.21e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   7 IVVFYLMFFAGAWMFiskRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELYFSM--VFLTFSVCEGALGLAVLVSIIRT 84
Cdd:MTH00107  8 IMLAFTISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMATLTILNTHFTLASMMpiILLVFAACEAAVGLALLVMVSNT 84

                        90
                ....*....|....
gi 58045512  85 HGNDYFHSISMLKC 98
Cdd:MTH00107 85 YGTDYVQNLNLLQC 98
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 8-97 7.29e-09

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 48.38  E-value: 7.29e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   8 VVFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGYELY--FSMVFLTFSVCEGALGLAVLVSIIRTH 85
Cdd:MTH00043  6 IIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVLLSRNH 85

                        90
                ....*....|..
gi 58045512  86 GNDYFHSISMLK 97
Cdd:MTH00043 86 NSDLVASLNLLQ 97
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 9-96 1.63e-05

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 39.93  E-value: 1.63e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 58045512   9 VFYLMFFAGAWMFISKRKHLLISLLSLEYMMLMLFMVIYLYLLIEGY--ELYFSMVFLTFSVCEGALGLAVLVSIIRTHG 86
Cdd:MTH00181  4 VFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNRTHG 83

                        90
                ....*....|
gi 58045512  87 NDYFHSISML 96
Cdd:MTH00181 84 SDHLLKFNLL 93
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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