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Conserved domains on  [gi|107122084|ref|YP_626378|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Elephas maximus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009569)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 1.54e-78

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214421  Cd Length: 175  Bit Score: 231.23  E-value: 1.54e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVLSAFLVGLLMEVFMVVWLFSGEHELVGFYFGGLESFVTLGEGGFEYVREDYSGGASLYSCGFWFLAMAGWML 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 107122084 161 FVSIFIATEITRKR 174
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 1.54e-78

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 231.23  E-value: 1.54e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVLSAFLVGLLMEVFMVVWLFSGEHELVGFYFGGLESFVTLGEGGFEYVREDYSGGASLYSCGFWFLAMAGWML 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 107122084 161 FVSIFIATEITRKR 174
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 1.06e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 64.45  E-value: 1.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   17 IGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAM-ATEEYPETWGSNVVVLSAFLVG 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 107122084   96 LLMEVFMVVWLFSGEHELVGFYFGGLESFVTLGEggfeyvredysggaSLYSCGFWFLAMAGWMLFVSIFIATEI 170
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGE--------------LLFTDYLLPFELASVLLLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00109
NADH dehydrogenase subunit 6; Provisional
 1-174 1.54e-78

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214421  Cd Length: 175  Bit Score: 231.23  E-value: 1.54e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00109   2 MMYIVFILSVLFVLGFVGFSSKPSPIYGGLGLIVSGGVGCGIVLSFGGSFLGLMVFLIYLGGMLVVFGYTTAMATEEYPE 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVLSAFLVGLLMEVFMVVWLFSGEHELVGFYFGGLESFVTLGEGGFEYVREDYSGGASLYSCGFWFLAMAGWML 160
Cdd:MTH00109  82 TWVSNKVVLGALLLGLLMELLLVLYVLKDDEVEVVFNFNGLGDWVIYDTGGSGFFSEDAMGVAALYSYGTWLVVVTGWSL 161

                        170
                 ....*....|....
gi 107122084 161 FVSIFIATEITRKR 174
Cdd:MTH00109 162 FIGVFVIIEITRGN 175
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-172 4.17e-36

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 123.33  E-value: 4.17e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVLSafLVGLLMEVFMVVWLFSGehelvGFYFGGLESFVTLGEggFEYVREDYSGGASLYSCGFWFLAMAGWML 160
Cdd:MTH00138  81 SWGSWSVLGY--VVGYLVGVVLAAGLFWG-----GWYEGSWVVVDELKE--FSVLRGDVGGVALMYSSGGGMLVICAWVL 151

                        170
                 ....*....|..
gi 107122084 161 FVSIFIATEITR 172
Cdd:MTH00138 152 LLTLFVVLELTR 163
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 1-172 2.41e-34

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 118.80  E-value: 2.41e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00065   1 MMYLGFLGMLGLVVGLVAVASNPSPYFAALGLVLGAVCGCLVLVELGVSFLSLVLFLIYLGGMLVVFAYSAALAAEPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVlsaFLVGLLMEVFMVVWLFSGEHELVGFYFGGlesfvtlGEGGFEYVREDYSGGASLYSCGFWFLAMAGWML 160
Cdd:MTH00065  81 AWGSWSVL---VYVLFYLLLLIVGYILFGCNFSLEFLFTN-------YDTEFSVVGYDWGGVGLMYSSGGWFLMISGWVL 150

                        170
                 ....*....|..
gi 107122084 161 FVSIFIATEITR 172
Cdd:MTH00065 151 LLTLFVVLEVTR 162
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-172 1.15e-29

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 106.76  E-value: 1.15e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVlsAFLVGLLMEVFMVVWLFSGEHELVGFyfggleSFVTLGEGGFEYVREDYSGGASLYSCGFWFLAMAGWML 160
Cdd:MTH00115  81 AWGDWGVV--GYVVGFVLVVVVVGVVVGGLWGMEGV------GVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGL 152

                        170
                 ....*....|..
gi 107122084 161 FVSIFIATEITR 172
Cdd:MTH00115 153 LLTLFVVLELVR 164
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 1-172 1.40e-15

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 70.02  E-value: 1.40e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00214   1 MLYFVFLLMFGFLLGLMMVASSPSPYFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAALAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVLSAFLVGLLMEVFMVvwlfsgehelvgFYFGGLESFVTLGEGGFEYVreDYSGGASLYSCGFWFLAMAGWML 160
Cdd:MTH00214  81 SWGGWSVLLFFLFYLLGLGFVGF------------YFYGGWEMLSWMGVDEANNL--DLSGVSDLYSRGFFLLLLGGVVL 146

                        170
                 ....*....|..
gi 107122084 161 FVSIFIATEITR 172
Cdd:MTH00214 147 FLVLFVVLELVR 158
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
17-170 1.06e-13

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 64.45  E-value: 1.06e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   17 IGFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAM-ATEEYPETWGSNVVVLSAFLVG 95
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEFLAAVQVLVYVGAIMVLFLFVIMLlLAEEEPEKLRSGLPLAALLLGL 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 107122084   96 LLMEVFMVVWLFSGEHELVGFYFGGLESFVTLGEggfeyvredysggaSLYSCGFWFLAMAGWMLFVSIFIATEI 170
Cdd:pfam00499  81 LLLALLLLVLLSASLTPAAAAAAPDVGNIEAIGE--------------LLFTDYLLPFELASVLLLVALVGAIVL 141
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 1-172 8.39e-09

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 51.83  E-value: 8.39e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   1 MMYIVFIMSVLYVVGFIGFSSkpSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMATEEYPE 80
Cdd:MTH00045   1 MVFYLFLILMLFGSTLVFYSL--SPYYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYSSALSAERYPS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084  81 TWGSNVVVLSAFLVGLLMevfmvvwlfsgehelvgfyFGGLESFVTLGEGGFE-YVREDYSGGASLYSCGFWFLAMAGWM 159
Cdd:MTH00045  79 VSNLGEVLVLSLLLSLWV-------------------FISFDNFLELSNNNWSlVSLSDLVGSSELYNSGGLYLLLGGFI 139

                        170
                 ....*....|...
gi 107122084 160 LFVSIFIATEITR 172
Cdd:MTH00045 140 LLVALVVALVISF 152
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 2-126 2.92e-04

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 39.22  E-value: 2.92e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 107122084   2 MYIVFIMSVLYVVGFIgFSSKPSPVYGGMSLVVSGGLGCGIIMSSGGSFLGLVVFLVYLGGMMVVFGYTIAMAteeyPET 81
Cdd:MTH00212   1 MLLSLLLSLLLLLMLL-FPLSAHPLTLGVSLLLSSLLSCLIITMESNSWYGYILFLIYIGGLLVLFGYMVALS----PNE 75

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 107122084  82 WGSNVVVLSAFLVGLLMEVFMVVWLFSGEHELVGFYFGGLESFVT 126
Cdd:MTH00212  76 HLFFKKYFKGFGMILISLNLYLLLMTLGSSNFSPMLNLKLELNVS 120
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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