2HIZ: Crystal Structure Of Human Beta-secretase (bace) In The Presence Of An Inhibitor

PDB ID: 2HIZDownload
MMDB ID: 43854
PDB Deposition Date: 2006/6/29
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 2HIZ: monomeric; determined by author
Molecular Components in 2HIZ
Label Count Molecule
Protein (1 molecule)
1
Beta-secretase 1
(Gene symbol: BACE1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
Phosphate IonPhosphate Ion
2
1
Benzyl [(1s)-2-({(1s,2r)-1-Benzyl-2-Hydroxy-3-[(3-Methoxybenzyl)amino]propyl}amino)-2-Oxo-1-{[(1-Propylbutyl)sulfonyl]methyl}ethyl]carbamateBenzyl [(1s)-2-({(1s,2r)-1-Benzyl-2-Hydroxy-3-[(3-Methoxybenzyl)amino]propyl}amino)-2-Oxo-1-{[(1-Propylbutyl)sulfonyl]methyl}ethyl]carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303