2NPP: Structure of the Protein Phosphatase 2A Holoenzyme

PDB ID: 2NPPDownload
MMDB ID: 84470
PDB Deposition Date: 2006/10/28
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 3.3  Å
Source Organism:
Similar Structures:
Biological Unit for 2NPP: tetrameric; determined by author and by software (PISA)
Molecular Components in 2NPP
Label Count Molecule
Proteins (3 molecules)
1
Protein Phosphatase 2, Regulatory Subunit a (PR 65), Alpha Isoform
(Gene symbol: PPP2R1A)
Molecule annotation
1
Serine/threonine-protein Phosphatase 2A 56 KDA Regulatory Subunit Gamma Isoform
(Gene symbol: PPP2R5C)
Molecule annotation
1
Serine/threonine-protein Phosphatase 2A Catalytic Subunit Alpha Isoform
(Gene symbol: PPP2CA)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
Y
1
microcystin LR
1
2
MANGANESE (II) IONMANGANESE (II) ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303