2Q8I: Pyruvate dehydrogenase kinase isoform 3 in complex with antitumor drug radicicol

PDB ID: 2Q8IDownload
MMDB ID: 54149
PDB Deposition Date: 2007/6/10
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 2Q8I: tetrameric; determined by author
Molecular Components in 2Q8I
Label Count Molecule
Proteins (4 molecules)
2
[pyruvate Dehydrogenase [lipoamide]] Kinase Isozyme 3
(Gene symbol: PDK3)
Molecule annotation
2
Dihydrolipoyllysine-residue Acetyltransferase Component of Pyruvate Dehydrogenase Complex
(Gene symbol: DLAT)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
POTASSIUM IONPOTASSIUM ION
2
2
RADICICOLRADICICOL
3
2
GLYCEROLGLYCEROL
4
2
DIHYDROLIPOIC ACIDDIHYDROLIPOIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303