2VAG: Crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor

PDB ID: 2VAGDownload
MMDB ID: 59824
PDB Deposition Date: 2007/8/31
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 2VAG: monomeric; determined by author and by software (PISA)
Molecular Components in 2VAG
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase Clk1
(Gene symbol: CLK1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylateethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303