3CU8: Impaired Binding Of 14-3-3 To Raf1 Is Linked To Noonan And Leopard Syndrome

PDB ID: 3CU8Download
MMDB ID: 72426
PDB Deposition Date: 2008/4/16
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3CU8: tetrameric; determined by author and by software (PISA)
Molecular Components in 3CU8
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Zeta/delta
(Gene symbol: YWHAZ)
Molecule annotation
2
RAF Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: RAF1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
Magnesium IonMagnesium Ion
2
1
Propanoic AcidPropanoic Acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303