3D4Q: Pyrazole-based inhibitors of B-Raf kinase

PDB ID: 3D4QDownload
MMDB ID: 66171
PDB Deposition Date: 2008/5/14
Updated in MMDB: 2010/09
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3D4Q: monomeric; determined by software (PISA)
Molecular Components in 3D4Q
Label Count Molecule
Protein (1 molecule)
1
B-raf Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: BRAF)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime(1E)-5-(1-piperidin-4-yl-3-pyridin-4-yl-1H-pyrazol-4-yl)-2,3-dihydro-1H-inden-1-one oxime
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303