3DXJ: Crystal structure of thermus thermophilus rna polymerase holoenzyme in complex with the antibiotic myxopyronin

PDB ID: 3DXJDownload
MMDB ID: 67337
PDB Deposition Date: 2008/7/24
Updated in MMDB: 2008/11
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
Similar Structures:
Biological Unit for 3DXJ: hexameric; determined by author and by software (PISA)
Molecular Components in 3DXJ
Label Count Molecule
Proteins (6 molecules)
2
DNA-directed RNA Polymerase Subunit Alpha; Chain A, B, K, L
(Gene symbol: TTHA1664)
Molecule annotation
1
Bacterial RNA Polymerase Beta Subunit; Chain C, M
(Gene symbol: rpoB)
Molecule annotation
1
Bacterial RNA Polymerase Beta-prime Subunit; Chain D, N
(Gene symbol: TTHA1812)
Molecule annotation
1
Bacterial RNA Polymerase Omega Subunit; Chain E, O
(Gene symbol: rpoZ)
Molecule annotation
1
RNA Polymerase Pricipal Sigma Factor (Rpod); Chain F, P
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
2
PHOSPHATE IONPHOSPHATE ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
4
2
ZINC IONZINC ION
5
1
methyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamatemethyl [(1E,5R)-5-{(3S)-3-[(2E,4E)-2,5-dimethylocta-2,4-dienoyl]-2,4-dioxo-3,4-dihydro-2H-pyran-6-yl}hexylidene]carbamate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303