3G60: Structure of P-glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding

PDB ID: 3G60Download
MMDB ID: 70432
PDB Deposition Date: 2009/2/5
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 4.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3G60: monomeric; determined by author and by software (PISA)
Molecular Components in 3G60
Label Count Molecule
Protein (1 molecule)
1
Multidrug Resistance Protein 1A
(Gene symbol: Abcb1a)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione(4R,11R,18R)-4,11,18-tri(propan-2-yl)-6,13,20-triselena-3,10,17,22,23,24-hexaazatetracyclo[17.2.1.1~5,8~.1~12,15~]tetracosa-1(21),5(24),7,12(23),14,19(22)-hexaene-2,9,16-trione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303