3IW4: Crystal structure of PKC alpha in complex with NVP-AEB071

PDB ID: 3IW4Download
MMDB ID: 77855
PDB Deposition Date: 2009/9/2
Updated in MMDB: 2024/12
Experimental Method:
x-ray diffraction
Resolution: 2.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3IW4: monomeric; determined by author and by software (PISA)
Molecular Components in 3IW4
Label Count Molecule
Protein (1 molecule)
1
Protein Kinase C Alpha Type
(Gene symbol: PRKCA)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]-1H-pyrrole-2,5-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303