3OXZ: Crystal structure of ABL kinase domain bound with a DFG-out inhibitor AP24534

PDB ID: 3OXZDownload
MMDB ID: 87374
PDB Deposition Date: 2010/9/22
Updated in MMDB: 2010/12
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 3OXZ: monomeric; determined by author and by software (PISA)
Molecular Components in 3OXZ
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Abl1
(Gene symbol: Abl1)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide3-(imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzam ide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303