NCBI
National Center for
Biotechnology Information
Search
3PP1:
Crystal Structure of the Human Mitogen-activated protein kinase kinase 1 (MEK 1) in complex with ligand and MgATP
PDB ID:
3PP1
Download
MMDB ID:
88850
PDB Deposition Date:
2010/11/23
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.7 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3PP1: monomeric; determined by author
Molecular Components in 3PP1
Label
Count
Molecule
Protein (1 molecule)
A
1
Dual Specificity Mitogen-activated Protein Kinase Kinase 1
(Gene symbol:
MAP2K1
)
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ADENOSINE-5'-TRIPHOSPHATE
2
1
MAGNESIUM ION
3
1
3-[(2R)-2,3-dihydroxypropyl]-6-fluoro-5-[(2-fluoro-4-iodophenyl)amino]-8-methylpyrido[2,3-d]pyrimidine-4,7(3H,8H)-dione
4
1
ACETATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303