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4A3G:
RNA Polymerase II initial transcribing complex with a 2nt DNA-RNA hybrid
PDB ID:
4A3G
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MMDB ID:
97136
PDB Deposition Date:
2011/9/30
Updated in MMDB:
2024/05
Experimental Method:
x-ray diffraction
Resolution:
3.5 Å
Source Organism:
Saccharomyces cerevisiae
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4A3G: 15-meric; determined by author and by software (PISA)
Molecular Components in 4A3G
Label
Count
Molecule
Proteins (12 molecules)
A
1
DNA-directed RNA Polymerase II Subunit Rpb1
(Gene symbol:
RPO21
)
B
1
DNA-directed RNA Polymerase II Subunit Rpb2
(Gene symbol:
RPB2
)
C
1
DNA-directed RNA Polymerase II Subunit Rpb3
(Gene symbol:
RPB3
)
D
1
DNA-directed RNA Polymerase II Subunit Rpb4
(Gene symbol:
RPB4
)
E
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 1
(Gene symbol:
RPB5
)
F
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 2
(Gene symbol:
RPO26
)
G
1
Rpb7, DNA-directed RNA Polymerase II Subunit Rpb7
(Gene symbol:
RPB7
)
H
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 3
(Gene symbol:
RPB8
)
I
1
DNA-directed RNA Polymerase II Subunit Rpb9
(Gene symbol:
RPB9
)
J
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 5
(Gene symbol:
RPB10
)
K
1
DNA-directed RNA Polymerase II Subunit Rpb11
(Gene symbol:
RPB11
)
L
1
DNA-directed RNA Polymerases I, II, and III Subunit Rpabc 4
(Gene symbol:
RPC10
)
Nucleotides(3 molecules)
N
1
NON Template DNA 5'-d(*gp*gp*cp*ap*cp*ap*ap*cp*tp*gp*cp *gp*cp*tp)-3'
P
1
Transcript RNA 5'-r(*cp*ap)-3'
T
1
Template DNA 5'-d(*ap*gp*cp*gp*cp*ap*gp*tp*tp*gp*tp*gp *cp*tp*ap*tp*gp*ap*brup*ap*tp*tp*tp*tp*tp*ap*dt)-3'
Chemicals and Non-standard biopolymers (9 molecules)
1
8
ZINC ION
2
1
MAGNESIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303