4ANP: Crystal structure of human phenylalanine hydroxylase in complex with a pharmacological chaperone

PDB ID: 4ANPDownload
MMDB ID: 98724
PDB Deposition Date: 2012/3/21
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.11  Å
Source Organism:
Similar Structures:
Biological Unit for 4ANP: monomeric; determined by author and by software (PISA)
Molecular Components in 4ANP
Label Count Molecule
Protein (1 molecule)
1
Phenylalanine-4-hydroxylase
(Gene symbol: PAH)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
FE (III) IONFE (III) ION
2
1
5,6-DIMETHYL-3-(4-METHYL-2-PYRIDINYL)-2-THIOXO-2,3-DIHYDROTHIENO[2,3- D]PYRIMIDIN-4(1H)-ONE5,6-DIMETHYL-3-(4-METHYL-2-PYRIDINYL)-2-THIOXO-2,3-DIHYDROTHIENO[2,3- D]PYRIMIDIN-4(1H)-ONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303