4JLG: SETD7 in complex with inhibitor (R)-PFI-2 and S-adenosyl-methionine

PDB ID: 4JLGDownload
MMDB ID: 109256
PDB Deposition Date: 2013/3/12
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.896  Å
Source Organism:
Similar Structures:
Biological Unit for 4JLG: monomeric; determined by software (PISA)
Molecular Components in 4JLG
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Setd7
(Gene symbol: SETD7)
Molecule annotation
Chemicals and Non-standard biopolymers (19 molecules)
1
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
2
1
8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide8-fluoro-N-{(2R)-1-oxo-1-(pyrrolidin-1-yl)-3-[3-(trifluoromethyl)phenyl]propan-2-yl}-1,2,3,4-tetrahydroisoquinoline-6-sulfonamide
3
17
Molecule information is not available.
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303