4M1C: Crystal Structure Analysis of Fab-Bound Human Insulin Degrading Enzyme (IDE) in Complex with Amyloid-Beta (1-40)

PDB ID: 4M1CDownload
MMDB ID: 122143
PDB Deposition Date: 2013/8/2
Updated in MMDB: 2014/10
Experimental Method:
x-ray diffraction
Resolution: 3.5007  Å
Source Organism:
Similar Structures:
Biological Unit for 4M1C: pentameric; determined by author
Molecular Components in 4M1C
Label Count Molecule
Proteins (5 molecules)
2
Insulin-degrading Enzyme
(Gene symbol: IDE)
Molecule annotation
1
Fab-bound Ide, Heavy Chain
Molecule annotation
1
Fab-bound Ide, Light Chain
Molecule annotation
1
Amyloid Beta A4 Protein
(Gene symbol: APP)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303