4NXS: Crystal structure of human alpha-galactosidase A in complex with 1-deoxygalactonojirimycin-pFPhT

PDB ID: 4NXSDownload
MMDB ID: 120624
PDB Deposition Date: 2013/12/9
Updated in MMDB: 2017/12
Experimental Method:
x-ray diffraction
Resolution: 2.5493  Å
Source Organism:
Similar Structures:
Biological Unit for 4NXS: dimeric; determined by author and by software (PISA)
Molecular Components in 4NXS
Label Count Molecule
Proteins (2 molecules)
2
Alpha-galactosidase a
(Gene symbol: GLA)
Molecule annotation
Chemicals and Non-standard biopolymers (15 molecules)
1
8
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
5
SULFATE IONSULFATE ION
3
2
(2R,3S,4R,5S)-N-(4-fluorophenyl)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidine-1-carbothioamide(2R,3S,4R,5S)-N-(4-fluorophenyl)-3,4,5-trihydroxy-2-(hydroxymethyl)piperidine-1-carbothioamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303