4TWT: Human TNFa dimer in complex with the semi-synthetic bicyclic peptide M21

PDB ID: 4TWTDownload
MMDB ID: 126722
PDB Deposition Date: 2014/7/1
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.85  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 4TWT: trimeric; determined by software (PISA)
Molecular Components in 4TWT
Label Count Molecule
Proteins (3 molecules)
2
Tumor Necrosis Factor
Molecule annotation
1
Ala-cys-pro-pro-cys-leu-trp-gln-val-leu-cys-gly
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
GLYCEROLGLYCEROL
2
1
(2,4,6-trimethylbenzene-1,3,5-triyl)trimethanol(2,4,6-trimethylbenzene-1,3,5-triyl)trimethanol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303