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4V0G:
Jak3 In Complex With A Covalent Egfr Inhibitor
PDB ID:
4V0G
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MMDB ID:
135319
PDB Deposition Date:
2014/9/16
Updated in MMDB:
2016/01
Experimental Method:
x-ray diffraction
Resolution:
3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 4V0G: monomeric; determined by software (PISA)
Molecular Components in 4V0G
Label
Count
Molecule
Protein (1 molecule)
A
1
Tyrosine-protein Kinase Jak3
(Gene symbol:
JAK3
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[3-(2-{3-Amino-6-[1-(1-Methylpiperidin-4-Yl)-1h-Pyrazol-4-Yl]pyrazin-2-Yl}-1h-Benzimidazol-1-Yl)phenyl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303