5A0Q: Cryo-EM reveals the conformation of a substrate analogue in the human 20S proteasome core

PDB ID: 5A0QDownload
MMDB ID: 135159
PDB Deposition Date: 2015/4/22
Updated in MMDB: 2015/12
Experimental Method:
electron microscopy
Resolution: 3.5  Å
Source Organism:
Similar Structures:
Biological Unit for 5A0Q: 28-meric; determined by author
Molecular Components in 5A0Q
Label Count Molecule
Proteins (28 molecules)
2
Proteasome Subunit Alpha Type-6
(Gene symbol: PSMA6)
Molecule annotation
2
Proteasome Subunit Alpha Type-2
(Gene symbol: PSMA2)
Molecule annotation
2
Proteasome Subunit Alpha Type-4
(Gene symbol: PSMA4)
Molecule annotation
2
Proteasome Subunit Alpha Type-7
(Gene symbol: PSMA7)
Molecule annotation
2
Proteasome Subunit Alpha Type-5
(Gene symbol: PSMA5)
Molecule annotation
2
Proteasome Subunit Alpha Type-1
(Gene symbol: PSMA1)
Molecule annotation
2
Proteasome Subunit Alpha Type-3
(Gene symbol: PSMA3)
Molecule annotation
2
Proteasome Subunit Beta Type-6
(Gene symbol: PSMB6)
Molecule annotation
2
Proteasome Subunit Beta Type-7
(Gene symbol: PSMB7)
Molecule annotation
2
Proteasome Subunit Beta Type-3
(Gene symbol: PSMB3)
Molecule annotation
2
Proteasome Subunit Beta Type-2
(Gene symbol: PSMB2)
Molecule annotation
2
Proteasome Subunit Beta Type-5
(Gene symbol: PSMB5)
Molecule annotation
2
Proteasome Subunit Beta Type-1
(Gene symbol: PSMB1)
Molecule annotation
2
Proteasome Subunit Beta Type-4
(Gene symbol: PSMB4)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
6
ADA-(AHX)3-(LEU)3-VINYL SULFONE (Link to PubChem not yet available)ADA-(AHX)3-(LEU)3-VINYL SULFONE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303