5ECE: Tankyrase 1 with Phthalazinone 1

PDB ID: 5ECEDownload
MMDB ID: 134474
PDB Deposition Date: 2015/10/20
Updated in MMDB: 2015/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5ECE: monomeric; determined by author and by software (PISA)
Molecular Components in 5ECE
Label Count Molecule
Protein (1 molecule)
1
Tankyrase-1
(Gene symbol: TNKS)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
2
1
2-[4-[3-[(4-oxidanylidene-3~{H}-phthalazin-1-yl)methyl]phenyl]carbonylpiperazin-1-yl]pyridine-3-carbonitrile2-[4-[3-[(4-oxidanylidene-3~{H}-phthalazin-1-yl)methyl]phenyl]carbonylpiperazin-1-yl]pyridine-3-carbonitrile
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303