5EDE: Human Pde10a In Complex With 1-(4-chloro-phenyl)-3-methyl-1h-thieno[2, 3-c]pyrazole-5-carboxylic Acid (tetrahydro-furan-2-ylmethyl)-amide At 2.2a

PDB ID: 5EDEDownload
MMDB ID: 137279
PDB Deposition Date: 2015/10/21
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 5EDE: monomeric; determined by author
Molecular Components in 5EDE
Label Count Molecule
Protein (1 molecule)
1
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol: PDE10A)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
Zinc IonZinc Ion
2
1
Magnesium IonMagnesium Ion
3
1
GlycerolGlycerol
4
1
1-(4-Chlorophenyl)-3-Methyl-~{n}-[[(2~{r})-Oxolan-2-Yl]methyl]thieno[2,3-C]pyrazole-5-Carboxamide1-(4-Chlorophenyl)-3-Methyl-~{n}-[[(2~{r})-Oxolan-2-Yl]methyl]thieno[2,3-C]pyrazole-5-Carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303