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5EDE:
Human Pde10a In Complex With 1-(4-chloro-phenyl)-3-methyl-1h-thieno[2, 3-c]pyrazole-5-carboxylic Acid (tetrahydro-furan-2-ylmethyl)-amide At 2.2a
PDB ID:
5EDE
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MMDB ID:
137279
PDB Deposition Date:
2015/10/21
Updated in MMDB:
2016/05
Experimental Method:
x-ray diffraction
Resolution:
2.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 5EDE: monomeric; determined by author
Molecular Components in 5EDE
Label
Count
Molecule
Protein (1 molecule)
A
1
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol:
PDE10A
)
Chemicals and Non-standard biopolymers (4 molecules)
1
1
Zinc Ion
2
1
Magnesium Ion
3
1
Glycerol
4
1
1-(4-Chlorophenyl)-3-Methyl-~{n}-[[(2~{r})-Oxolan-2-Yl]methyl]thieno[2,3-C]pyrazole-5-Carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303