5FZ1: Crystal structure of the catalytic domain of human JARID1B in complex with Maybridge fragment 2,4-dichloro-N-pyridin-3-ylbenzamide (E48115b) (ligand modelled based on PANDDA event map)

PDB ID: 5FZ1Download
MMDB ID: 138961
PDB Deposition Date: 2016/3/10
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 2.39  Å
Source Organism:
Similar Structures:
Biological Unit for 5FZ1: monomeric; determined by author and by software (PISA)
Molecular Components in 5FZ1
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5B, Lysine-specific Demethylase 5B
(Gene symbol: KDM5B)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
2
ZINC IONZINC ION
2
3
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
3
1
MANGANESE (II) IONMANGANESE (II) ION
4
1
PHOSPHATE IONPHOSPHATE ION
5
12
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
2,4-dichloro-N-(pyridin-3-yl)benzamide2,4-dichloro-N-(pyridin-3-yl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303