5HSR: Fluorine substituted 5-methyl-6-(3',4'-difluoromethoxyphenythio)thieno[2,3-d]pyrimidine-2,4-diamine

PDB ID: 5HSRDownload
MMDB ID: 146941
PDB Deposition Date: 2016/1/26
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.21  Å
Source Organism:
Similar Structures:
Biological Unit for 5HSR: monomeric; determined by author and by software (PISA)
Molecular Components in 5HSR
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
(Gene symbol: DHFR)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
2
5-methyl-6-[(2,3,4-trifluorophenyl)sulfanyl]thieno[2,3-d]pyrimidine-2,4-diamine5-methyl-6-[(2,3,4-trifluorophenyl)sulfanyl]thieno[2,3-d]pyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303