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5I2R:
Human Pde10a In Complex With 3-(2-phenylpyrazol-3-yl)-1-[3- (trifluoromethoxy)phenyl]pyridazin-4-one
PDB ID:
5I2R
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MMDB ID:
137355
PDB Deposition Date:
2016/2/9
Updated in MMDB:
2016/05
Experimental Method:
x-ray diffraction
Resolution:
2.5 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 5I2R: monomeric; determined by author
Molecular Components in 5I2R
Label
Count
Molecule
Protein (1 molecule)
A
1
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol:
PDE10A
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Zinc Ion
2
1
Magnesium Ion
3
1
3-(1-Phenyl-1h-Pyrazol-5-Yl)-1-[3-(Trifluoromethoxy)phenyl]pyridazin-4(1h)-One
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303