5I2R: Human Pde10a In Complex With 3-(2-phenylpyrazol-3-yl)-1-[3- (trifluoromethoxy)phenyl]pyridazin-4-one

PDB ID: 5I2RDownload
MMDB ID: 137355
PDB Deposition Date: 2016/2/9
Updated in MMDB: 2016/05
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 5I2R: monomeric; determined by author
Molecular Components in 5I2R
Label Count Molecule
Protein (1 molecule)
1
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol: PDE10A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Zinc IonZinc Ion
2
1
Magnesium IonMagnesium Ion
3
1
3-(1-Phenyl-1h-Pyrazol-5-Yl)-1-[3-(Trifluoromethoxy)phenyl]pyridazin-4(1h)-One3-(1-Phenyl-1h-Pyrazol-5-Yl)-1-[3-(Trifluoromethoxy)phenyl]pyridazin-4(1h)-One
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303