5JO0: Structure of Plasmodium falciparum DXR in complex with a beta-substituted fosmidomycin analogue, LC56 and manganese

PDB ID: 5JO0Download
MMDB ID: 142291
PDB Deposition Date: 2016/5/1
Updated in MMDB: 2016/10
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 5JO0: dimeric; determined by author and by software (PISA)
Molecular Components in 5JO0
Label Count Molecule
Proteins (2 molecules)
2
1-deoxy-d-xylulose 5-phosphate Reductoisomerase, Apicoplastic
(Gene symbol: PF3D7_1467300)
Molecule annotation
Chemicals and Non-standard biopolymers (17 molecules)
1
2
[(2R)-2-{2-[hydroxy(methyl)amino]-2-oxoethyl}-5-(3-methylphenyl)pentyl]phosphonic acid[(2R)-2-{2-[hydroxy(methyl)amino]-2-oxoethyl}-5-(3-methylphenyl)pentyl]phosphonic acid
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
4
GLYCEROLGLYCEROL
4
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
morpholinemorpholine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303