National Center for
Biotechnology Information

5L5Q: Yeast 20S proteasome with human beta5i (1-138) and human beta6 (97-111; 118-133) in complex with epoxyketone 18

PDB ID:

MMDB ID:

144789

PDB Deposition Date:

2016/5/28

Updated in MMDB:

2016/12

Experimental Method:

x-ray diffraction

Resolution:

2.8 Å

Source Organism:

Saccharomyces cerevisiae S288C▼

Taxonomy	Molecule
Saccharomyces cerevisiae S288C	A, B, C, D, E, F, G, H, I, J, M, N, O, P, Q, R, S, T, U, V, W, X, a, b
synthetic construct	K, L, Y, Z

Similar Structures:

Biological Unit for 5L5Q: 28-meric; determined by author

Molecular Components in 5L5Q
Label	Count	Molecule
Proteins (28 molecules)
A O	2	Proteasome Subunit Alpha Type-2
B P	2	Proteasome Subunit Alpha Type-3
C Q	2	Proteasome Subunit Alpha Type-4
D R	2	Proteasome Subunit Alpha Type-5
E S	2	Proteasome Subunit Alpha Type-6
F T	2	Probable Proteasome Subunit Alpha Type-7
G U	2	Proteasome Subunit Alpha Type-1
H V	2	Proteasome Subunit Beta Type-2
I W	2	Proteasome Subunit Beta Type-3
J X	2	Proteasome Subunit Beta Type-4
K Y	2	Proteasome Subunit Beta Type-8,proteasome Subunit Beta Type-5
L Z	2	Proteasome Subunit Beta Type-6,proteasome Subunit Beta Type-6,proteasome Subunit Beta Type-6,proteasome Subunit Beta Type-6,proteasome Subunit Beta Type-6
M a	2	Proteasome Subunit Beta Type-7
N b	2	Proteasome Subunit Beta Type-1
Chemicals and Non-standard biopolymers (13 molecules)
1	8	MAGNESIUM ION
2	2	CHLORIDE ION
3	2	~{N}-[(2~{R})-1-[[(2~{S})-3-(4-methoxyphenyl)-1-[[(2~{S},3~{S},4~{R})-4-methyl-3,5-bis(oxidanyl)-1-phenyl-pentan-2-yl]amino]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-propan-2-yl]-1-methyl-5~{H}-indene-2-carboxamide
4	1	2-(N-MORPHOLINO)-ETHANESULFONIC ACID

* Click molecule labels to explore molecular sequence information.

Citing MMDB