5LSU: Structure of the Epigenetic Oncogene MMSET and inhibition by N-Alkyl Sinefungin Derivatives

PDB ID: 5LSUDownload
MMDB ID: 143844
PDB Deposition Date: 2016/9/5
Updated in MMDB: 2016/12
Experimental Method:
x-ray diffraction
Resolution: 2.14  Å
Source Organism:
Similar Structures:
Biological Unit for 5LSU: monomeric; determined by author
Molecular Components in 5LSU
Label Count Molecule
Protein (1 molecule)
1
Histone-lysine N-methyltransferase Nsd2
(Gene symbol: NSD2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
3
ZINC IONZINC ION
2
1
S-ADENOSYLMETHIONINES-ADENOSYLMETHIONINE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303