5LV5: Crystal structure of mouse PRMT6 in complex with inhibitor LH1458

PDB ID: 5LV5Download
MMDB ID: 154571
PDB Deposition Date: 2016/9/12
Updated in MMDB: 2017/10
Experimental Method:
x-ray diffraction
Resolution: 1.802  Å
Source Organism:
Similar Structures:
Biological Unit for 5LV5: dimeric; determined by author and by software (PISA)
Molecular Components in 5LV5
Label Count Molecule
Proteins (2 molecules)
2
Protein Arginine N-methyltransferase 6
(Gene symbol: Prmt6)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]-[(3~{S})-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]azanium2-[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]ethyl-[[4-azanyl-1-(methoxymethyl)-2-oxidanylidene-pyrimidin-5-yl]methyl]-[(3~{S})-3-azanyl-4-oxidanyl-4-oxidanylidene-butyl]azanium
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303