5NFP: Glucocorticoid Receptor in complex with budesonide

PDB ID: 5NFPDownload
MMDB ID: 154921
PDB Deposition Date: 2017/3/15
Updated in MMDB: 2018/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 5NFP: dimeric; determined by author and by software (PISA)
Molecular Components in 5NFP
Label Count Molecule
Proteins (2 molecules)
1
Glucocorticoid Receptor
(Gene symbol: NR3C1)
Molecule annotation
1
Nuclear Receptor Coactivator 2
(Gene symbol: NCOA2)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE
2
1
1,2-ETHANEDIOL1,2-ETHANEDIOL
3
1
GLYCEROLGLYCEROL
4
1
(1~{S},2~{S},4~{R},6~{R},8~{S},9~{S},11~{S},12~{S},13~{R})-9,13-dimethyl-11-oxidanyl-8-(2-oxidanylethanoyl)-6-propyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one(1~{S},2~{S},4~{R},6~{R},8~{S},9~{S},11~{S},12~{S},13~{R})-9,13-dimethyl-11-oxidanyl-8-(2-oxidanylethanoyl)-6-propyl-5,7-dioxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icosa-14,17-dien-16-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303