5OHI: Crystal structure of autotaxin in complex with BI-2545

PDB ID: 5OHIDownload
MMDB ID: 157864
PDB Deposition Date: 2017/7/17
Updated in MMDB: 2018/10
Experimental Method:
x-ray diffraction
Resolution: 1.66  Å
Source Organism:
Similar Structures:
Biological Unit for 5OHI: monomeric; determined by author and by software (PISA)
Molecular Components in 5OHI
Label Count Molecule
Protein (1 molecule)
1
Ectonucleotide Pyrophosphatase/phosphodiesterase Family Member 2
(Gene symbol: Enpp2)
Molecule annotation
Chemicals and Non-standard biopolymers (20 molecules)
1
6
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
beta-D-mannopyranosebeta-D-mannopyranose
3
4
alpha-D-mannopyranosealpha-D-mannopyranose
4
2
ZINC IONZINC ION
5
2
CALCIUM IONCALCIUM ION
6
1
SODIUM IONSODIUM ION
7
1
POTASSIUM IONPOTASSIUM ION
8
1
3,6,9,12,15-PENTAOXAHEPTADECANE3,6,9,12,15-PENTAOXAHEPTADECANE
9
1
CHLORIDE IONCHLORIDE ION
10
1
[3,5-bis(trifluoromethyl)phenyl]methyl (1~{S},5~{R})-6-[(1~{H}-benzotriazol-5-ylcarbonylamino)methyl]-3-azabicyclo[3.1.0]hexane-3-carboxylate[3,5-bis(trifluoromethyl)phenyl]methyl (1~{S},5~{R})-6-[(1~{H}-benzotriazol-5-ylcarbonylamino)methyl]-3-azabicyclo[3.1.0]hexane-3-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303