5VII: Crystal structure of GluN1/GluN2A NMDA receptor agonist binding domains with glycine and antagonist, 4-(3-fluoropropyl)phenyl-ACEPC

PDB ID: 5VIIDownload
MMDB ID: 150195
PDB Deposition Date: 2017/4/16
Updated in MMDB: 2023/10
Experimental Method:
x-ray diffraction
Resolution: 1.951  Å
Source Organism:
Similar Structures:
Biological Unit for 5VII: dimeric; determined by author and by software (PISA)
Molecular Components in 5VII
Label Count Molecule
Proteins (2 molecules)
1
Glutamate Receptor Ionotropic, Nmda 1
(Gene symbol: Grin1)
Molecule annotation
1
Glutamate Receptor Ionotropic, Nmda 2A
(Gene symbol: Grin2a)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
GLYCINEGLYCINE
2
1
5-[(2R)-2-amino-2-carboxyethyl]-1-[4-(3-fluoropropyl)phenyl]-1H-pyrazole-3-carboxylic acid5-[(2R)-2-amino-2-carboxyethyl]-1-[4-(3-fluoropropyl)phenyl]-1H-pyrazole-3-carboxylic acid
3
1
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
4
1
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303