5ZKB: Crystal structure of rationally thermostabilized M2 muscarinic acetylcholine receptor bound with AF-DX 384

PDB ID: 5ZKBDownload
MMDB ID: 168843
PDB Deposition Date: 2018/3/23
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.95  Å
Source Organism:
Similar Structures:
Biological Unit for 5ZKB: monomeric; determined by author
Molecular Components in 5ZKB
Label Count Molecule
Protein (1 molecule)
1
Muscarinic Acetylcholine Receptor M2,apo-cytochrome B562,muscarinic Acetylcholine Receptor M2
(Gene symbol: CHRM2)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-[2-[(2S)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxidanylidene-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamideN-[2-[(2S)-2-[(dipropylamino)methyl]piperidin-1-yl]ethyl]-6-oxidanylidene-5H-pyrido[2,3-b][1,4]benzodiazepine-11-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303