6E9W: Crystal structure of Rock1 with a pyridinylbenzamide based inhibitor

PDB ID: 6E9WDownload
MMDB ID: 168696
PDB Deposition Date: 2018/8/1
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.96  Å
Source Organism:
Similar Structures:
Biological Unit for 6E9W: dimeric; determined by author and by software (PISA)
Molecular Components in 6E9W
Label Count Molecule
Proteins (2 molecules)
2
Rho-associated Protein Kinase 1
(Gene symbol: ROCK1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
N-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamideN-[(2,3-dihydro-1,4-benzodioxin-5-yl)methyl]-4-(pyridin-4-yl)benzamide
2
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303