6EJ0: Crystal structure of KDM5B in complex with KDOPZ000049a

PDB ID: 6EJ0Download
MMDB ID: 161551
PDB Deposition Date: 2017/9/19
Updated in MMDB: 2018/05
Experimental Method:
x-ray diffraction
Resolution: 2.06  Å
Source Organism:
Similar Structures:
Biological Unit for 6EJ0: monomeric; determined by author and by software (PISA)
Molecular Components in 6EJ0
Label Count Molecule
Protein (1 molecule)
1
Lysine-specific Demethylase 5b,lysine-specific Demethylase 5B
(Gene symbol: KDM5B)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
ZINC IONZINC ION
2
2
MANGANESE (II) IONMANGANESE (II) ION
3
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
4
5
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
5
1
7-oxidanylidene-6-propan-2-yl-5-[1-(1-prop-2-enoylpiperidin-4-yl)pyrazol-4-yl]-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile7-oxidanylidene-6-propan-2-yl-5-[1-(1-prop-2-enoylpiperidin-4-yl)pyrazol-4-yl]-6~{H}-pyrazolo[1,5-a]pyrimidine-3-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303