6EZO: Eukaryotic initiation factor EIF2B in complex with ISRIB

PDB ID: 6EZODownload
MMDB ID: 160638
PDB Deposition Date: 2017/11/16
Updated in MMDB: 2019/12
Experimental Method:
electron microscopy
Resolution: 4.1  Å
Source Organism:
Similar Structures:
Biological Unit for 6EZO: decameric; determined by software (PISA)
Molecular Components in 6EZO
Label Count Molecule
Proteins (10 molecules)
2
Translation Initiation Factor Eif-2b Subunit Alpha
(Gene symbol: EIF2B1)
Molecule annotation
2
Translation Initiation Factor Eif-2b Subunit Beta
(Gene symbol: EIF2B2)
Molecule annotation
2
Translation Initiation Factor Eif-2b Subunit Gamma
(Gene symbol: EIF2B3)
Molecule annotation
2
Translation Initiation Factor Eif-2b Subunit Delta
(Gene symbol: EIF2B4)
Molecule annotation
2
Human Eukaryotic Initiation Factor Eif2b Epsilon Subunits
(Gene symbol: EIF2B5)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide2-(4-chloranylphenoxy)-~{N}-[4-[2-(4-chloranylphenoxy)ethanoylamino]cyclohexyl]ethanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303