6FZ5: Human N-myristoyltransferase (NMT1) with Myristoyl-CoA and inhibitor bound

PDB ID: 6FZ5Download
MMDB ID: 173609
PDB Deposition Date: 2018/3/14
Updated in MMDB: 2019/08
Experimental Method:
x-ray diffraction
Resolution: 1.89  Å
Source Organism:
Similar Structures:
Biological Unit for 6FZ5: monomeric; determined by author
Molecular Components in 6FZ5
Label Count Molecule
Protein (1 molecule)
1
Glycylpeptide N-tetradecanoyltransferase 1
(Gene symbol: NMT1)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
4-[3-[(8~{a}~{R})-3,4,6,7,8,8~{a}-hexahydro-1~{H}-pyrrolo[1,2-a]pyrazin-2-yl]propyl]-2,6-bis(chloranyl)-~{N}-methyl-~{N}-(1,3,5-trimethylpyrazol-4-yl)benzenesulfonamide4-[3-[(8~{a}~{R})-3,4,6,7,8,8~{a}-hexahydro-1~{H}-pyrrolo[1,2-a]pyrazin-2-yl]propyl]-2,6-bis(chloranyl)-~{N}-methyl-~{N}-(1,3,5-trimethylpyrazol-4-yl)benzenesulfonamide
2
1
TETRADECANOYL-COATETRADECANOYL-COA
3
1
MAGNESIUM IONMAGNESIUM ION
4
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303