NCBI
National Center for
Biotechnology Information
Search
6HXH:
Structure of the human ATP citrate lyase holoenzyme in complex with citrate, coenzyme A and Mg.ADP
PDB ID:
6HXH
Download
MMDB ID:
174136
PDB Deposition Date:
2018/10/17
Updated in MMDB:
2019/05
Experimental Method:
x-ray diffraction
Resolution:
3.3 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 6HXH: tetrameric; determined by software (PISA)
Molecular Components in 6HXH
Label
Count
Molecule
Proteins (4 molecules)
A
B
C
D
4
Atp-citrate Synthase,human ATP Citrate Lyase
(Gene symbol:
ACLY
)
Chemicals and Non-standard biopolymers (24 molecules)
1
8
MAGNESIUM ION
2
4
PHOSPHATE ION
3
4
CITRATE ANION
4
4
COENZYME A
5
4
ADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303