6ICJ: Crystal structure of PPARgamma with compound BR102375K

PDB ID: 6ICJDownload
MMDB ID: 179260
PDB Deposition Date: 2018/9/6
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.483  Å
Source Organism:
Similar Structures:
Biological Unit for 6ICJ: dimeric; determined by author and by software (PISA)
Molecular Components in 6ICJ
Label Count Molecule
Proteins (2 molecules)
1
Peroxisome Proliferator-activated Receptor Gamma
(Gene symbol: PPARG)
Molecule annotation
1
Nuclear Receptor Coactivator 1
(Gene symbol: NCOA1)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
GLYCEROLGLYCEROL
2
1
2-butyl-5-[(3-tert-butyl-1,2,4-oxadiazol-5-yl)methyl]-6-methyl-3-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}pyrimidin-4(3H)-one2-butyl-5-[(3-tert-butyl-1,2,4-oxadiazol-5-yl)methyl]-6-methyl-3-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl]methyl}pyrimidin-4(3H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303