6KDX: Crystal structure of PDE10A in complex with a triazolopyrimidine inhibitor

PDB ID: 6KDXDownload
MMDB ID: 178466
PDB Deposition Date: 2019/7/3
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.44  Å
Source Organism:
Similar Structures:
Biological Unit for 6KDX: monomeric; determined by author
Molecular Components in 6KDX
Label Count Molecule
Protein (1 molecule)
1
Camp and Camp-inhibited Cgmp 3',5'-cyclic Phosphodiesterase 10A
(Gene symbol: PDE10A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
ZINC IONZINC ION
2
1
MAGNESIUM IONMAGNESIUM ION
3
1
N-[2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)ethyl]quinolin-2-amineN-[2-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)ethyl]quinolin-2-amine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303