6NZD: Cryo-EM Structure of the Lysosomal Folliculin Complex (FLCN-FNIP2-RagA-RagC-Ragulator)

PDB ID: 6NZDDownload
MMDB ID: 181064
PDB Deposition Date: 2019/2/13
Updated in MMDB: 2019/12
Experimental Method:
electron microscopy
Resolution: 3.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6NZD: nonameric; determined by author and by software (PISA)
Molecular Components in 6NZD
Label Count Molecule
Proteins (9 molecules)
1
Ragulator Complex Protein Lamtor1
(Gene symbol: LAMTOR1)
Molecule annotation
1
Ragulator Complex Protein Lamtor2
(Gene symbol: LAMTOR2)
Molecule annotation
1
Ragulator Complex Protein Lamtor3
(Gene symbol: LAMTOR3)
Molecule annotation
1
Ragulator Complex Protein Lamtor4
(Gene symbol: LAMTOR4)
Molecule annotation
1
Hepatitis B Virus X Interacting Protein
(Gene symbol: LAMTOR5)
Molecule annotation
1
Ras-related Gtp-binding Protein a
(Gene symbol: RRAGA)
Molecule annotation
1
Ras-related Gtp-binding Protein C
(Gene symbol: RRAGC)
Molecule annotation
1
Folliculin
(Gene symbol: FLCN)
Molecule annotation
1
Folliculin-interacting Protein 2
(Gene symbol: FNIP2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
GUANOSINE-5'-DIPHOSPHATEGUANOSINE-5'-DIPHOSPHATE
2
1
9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione9-{5-O-[(S)-hydroxy{[(R)-hydroxy(thiophosphonooxy)phosphoryl]oxy}phosphoryl]-alpha-L-arabinofuranosyl}-3,9-dihydro-1H-purine-2,6-dione
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303