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6P9F:
Crystal structure of RAR-related orphan receptor C (NHIS-RORGT(244-487)-L6-SRC1(678-692)) in complex with a phenyl (3-phenylpyrrolidin-3-yl)sulfone inhibitor
PDB ID:
6P9F
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MMDB ID:
177525
PDB Deposition Date:
2019/6/10
Updated in MMDB:
2023/10
Experimental Method:
x-ray diffraction
Resolution:
2.8 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
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Biological Unit for 6P9F: monomeric; determined by author
Molecular Components in 6P9F
Label
Count
Molecule
Protein (1 molecule)
A
1
Nuclear Receptor Ror-gamma, Nuclear Receptor Coactivator 1 Chimera
(Gene symbol:
RORC
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
trans-4-{(3R)-3-[(4-fluorophenyl)sulfonyl]-3-[4-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)phenyl]pyrrolidine-1-carbonyl}cyclohexane-1-carboxylic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303