6PWV: Cryo-EM structure of MLL1 core complex bound to the nucleosome

PDB ID: 6PWVDownload
MMDB ID: 182357
PDB Deposition Date: 2019/7/23
Updated in MMDB: 2019/12
Experimental Method:
electron microscopy
Resolution: 6.2  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 6PWV: hexadecameric; determined by author
Molecular Components in 6PWV
Label Count Molecule
Proteins (14 molecules)
1
Retinoblastoma-binding Protein 5
Molecule annotation
1
WD Repeat-containing Protein 5
Molecule annotation
1
Histone-lysine N-methyltransferase 2A
Molecule annotation
2
Histone H3.2
Molecule annotation
2
Histone H4
Molecule annotation
2
Histone H2A Type 1
Molecule annotation
2
Histone H2B 1.1
Molecule annotation
2
Protein Dpy-30 Homolog
Molecule annotation
1
Set1/ash2 Histone Methyltransferase Complex Subunit Ash2
Molecule annotation
Nucleotides(2 molecules)
1
DNA (147-mer)
Molecule annotation
1
DNA (147-mer)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
S-ADENOSYL-L-HOMOCYSTEINES-ADENOSYL-L-HOMOCYSTEINE
2
2
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303