6QBG: Crystal structure of human cathepsin D in complex with macrocyclic inhibitor 14

PDB ID: 6QBGDownload
MMDB ID: 183513
PDB Deposition Date: 2018/12/21
Updated in MMDB: 2020/03
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 6QBG: dimeric; determined by author and by software (PISA)
Molecular Components in 6QBG
Label Count Molecule
Proteins (2 molecules)
1
Cathepsin D
(Gene symbol: CTSD)
Molecule annotation
1
Cathepsin D
(Gene symbol: CTSD)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
3
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
2
(3~{S},7~{S},8~{S})-8-(naphthalen-2-ylmethyl)-7-oxidanyl-3-propan-2-yl-1,4,9-triazacyclohenicosane-2,5,10-trione(3~{S},7~{S},8~{S})-8-(naphthalen-2-ylmethyl)-7-oxidanyl-3-propan-2-yl-1,4,9-triazacyclohenicosane-2,5,10-trione
3
2
DIMETHYL SULFOXIDEDIMETHYL SULFOXIDE
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303