6RL4: Fragment AZ-025 binding at the p53pT387/14-3-3 sigma interface

PDB ID: 6RL4Download
MMDB ID: 188983
PDB Deposition Date: 2019/5/1
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 6RL4: tetrameric; determined by author and by software (PISA)
Molecular Components in 6RL4
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Cellular Tumor Antigen P53
(Gene symbol: TP53)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
4
MAGNESIUM IONMAGNESIUM ION
2
2
CHLORIDE IONCHLORIDE ION
3
2
5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide5-[1-(2-azanylethyl)imidazol-4-yl]-4-phenyl-thiophene-2-carboximidamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303