6RWU: Fragment AZ-010 binding at the p53pT387/14-3-3 sigma interface

PDB ID: 6RWUDownload
MMDB ID: 188991
PDB Deposition Date: 2019/6/6
Updated in MMDB: 2020/07
Experimental Method:
x-ray diffraction
Resolution: 1.46  Å
Source Organism:
Similar Structures:
Biological Unit for 6RWU: tetrameric; determined by author and by software (PISA)
Molecular Components in 6RWU
Label Count Molecule
Proteins (4 molecules)
2
14-3-3 Protein Sigma
(Gene symbol: SFN)
Molecule annotation
2
Cellular Tumor Antigen P53
(Gene symbol: TP53)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
~{N}-[3-(5-carbamimidoylthiophen-3-yl)phenyl]propanamide~{N}-[3-(5-carbamimidoylthiophen-3-yl)phenyl]propanamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303