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6TLJ:
Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution
PDB ID:
6TLJ
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MMDB ID:
184441
PDB Deposition Date:
2019/12/2
Updated in MMDB:
2020/06
Experimental Method:
electron microscopy
Resolution:
3.8 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Molecular Components in 6TLJ
Label
Count
Molecule
Proteins (23 molecules)
A
1
Anaphase-promoting Complex Subunit 1
(Gene symbol:
ANAPC1
)
B
1
Anaphase-promoting Complex Subunit 11
(Gene symbol:
ANAPC11
)
C
P
2
Cell Division Cycle Protein 23 Homolog
(Gene symbol:
CDC23
)
D
1
Anaphase-promoting Complex Subunit 15
(Gene symbol:
ANAPC15
)
E
1
Anaphase-promoting Complex Subunit 16
(Gene symbol:
ANAPC16
)
F
H
2
Cell Division Cycle Protein 27 Homolog
(Gene symbol:
CDC27
)
G
W
2
Anaphase-promoting Complex Subunit Cdc26
(Gene symbol:
CDC26
)
I
1
Anaphase-promoting Complex Subunit 4
(Gene symbol:
ANAPC4
)
J
K
2
Cell Division Cycle Protein 16 Homolog
(Gene symbol:
CDC16
)
L
1
Anaphase-promoting Complex Subunit 10
(Gene symbol:
ANAPC10
)
M
1
Anaphase-promoting Complex Subunit 13
(Gene symbol:
ANAPC13
)
N
1
Anaphase-promoting Complex Subunit 2
(Gene symbol:
ANAPC2
)
O
1
Anaphase-promoting Complex Subunit 5
(Gene symbol:
ANAPC5
)
Q
1
Cell Division Cycle Protein 20 Homolog
(Gene symbol:
CDC20
)
R
1
Cell Division Cycle Protein 20 Homolog
(Gene symbol:
CDC20
)
S
1
Mitotic Checkpoint Serine/threonine-protein Kinase Bub1 Beta
(Gene symbol:
BUB1B
)
X
Y
2
Anaphase-promoting Complex Subunit 7
(Gene symbol:
ANAPC7
)
Z
1
Mitotic Spindle Assembly Checkpoint Protein Mad2a
(Gene symbol:
MAD2L1
)
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303