6TLJ: Cryo-EM structure of the Anaphase-promoting complex/Cyclosome, in complex with the Mitotic checkpoint complex (APC/C-MCC) at 3.8 angstrom resolution

PDB ID: 6TLJDownload
MMDB ID: 184441
PDB Deposition Date: 2019/12/2
Updated in MMDB: 2024/10
Experimental Method:
electron microscopy
Resolution: 3.8  Å
Source Organism:
Similar Structures:
Molecular Components in 6TLJ
Label Count Molecule
Proteins (23 molecules)
1
Anaphase-promoting Complex Subunit 1
(Gene symbol: ANAPC1)
Molecule annotation
1
Anaphase-promoting Complex Subunit 11
(Gene symbol: ANAPC11)
Molecule annotation
2
Cell Division Cycle Protein 23 Homolog
(Gene symbol: CDC23)
Molecule annotation
1
Anaphase-promoting Complex Subunit 15
(Gene symbol: ANAPC15)
Molecule annotation
1
Anaphase-promoting Complex Subunit 16
(Gene symbol: ANAPC16)
Molecule annotation
2
Cell Division Cycle Protein 27 Homolog
(Gene symbol: CDC27)
Molecule annotation
2
Anaphase-promoting Complex Subunit Cdc26
(Gene symbol: CDC26)
Molecule annotation
1
Anaphase-promoting Complex Subunit 4
(Gene symbol: ANAPC4)
Molecule annotation
2
Cell Division Cycle Protein 16 Homolog
(Gene symbol: CDC16)
Molecule annotation
1
Anaphase-promoting Complex Subunit 10
(Gene symbol: ANAPC10)
Molecule annotation
1
Anaphase-promoting Complex Subunit 13
(Gene symbol: ANAPC13)
Molecule annotation
1
Anaphase-promoting Complex Subunit 2
(Gene symbol: ANAPC2)
Molecule annotation
1
Anaphase-promoting Complex Subunit 5
(Gene symbol: ANAPC5)
Molecule annotation
1
Cell Division Cycle Protein 20 Homolog
(Gene symbol: CDC20)
Molecule annotation
1
Cell Division Cycle Protein 20 Homolog
(Gene symbol: CDC20)
Molecule annotation
1
Mitotic Checkpoint Serine/threonine-protein Kinase Bub1 Beta
(Gene symbol: BUB1B)
Molecule annotation
2
Anaphase-promoting Complex Subunit 7
(Gene symbol: ANAPC7)
Molecule annotation
1
Mitotic Spindle Assembly Checkpoint Protein Mad2a
(Gene symbol: MAD2L1)
Molecule annotation
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303